Hortus Malabaricus-s a comprehensive treatise that deals with the medicinal properties of the flora in the Indian state of Kerala. Originally written in Latin, it was compiled over a period of nearly 30 years and published from Amsterdam during 1678-1693.

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A page from the Preface to the book in which names of Carmelite Father Joannis Matthaei, the Brahmin physicians Ranga Bhat, Vinayaka Pandit, and Appu Bhatand the Ayurveda vaiya Itti Achuthan can be seen

The cover page of the original Latin edition of Hortus Malabaricus
Hortus Malabaricus (meaning Garden of Malabar) is a comprehensive treatise that deals with the medicinal properties of the flora in the Indian state of Kerala. Originally written in Latin, it was compiled over a period of nearly 30 years and published from Amsterdam during 1678-1693. The book was conceived by Hendrik van Rheede, who was the Governor of the Dutch administration in Kochi (formerly Cochin) at the time. The book has since been translated by Dr. K. S. Manilal intoEnglish and Malayalam.
Van Rheede is said to have taken a keen personal interest in the compilation of the Hortus Malabaricus. The work was edited by a team of nearly a hundred including physicians [such as Ranga Bhat, Vinayaka Pandit and Appu Bhat] professors of medicine and botany, amateur botanists (such as Arnold Seyn, Theodore Jansson of Almeloveen, Paul Hermann, Johannes Munnicks, Joannes Commelinus, Abraham a Poot), and technicians, illustrators and engravers, together with the collaboration of company officials, clergymen (D. John Caesarius and Carmelite Mathaeus of St. Joseph). Van Rheede was also assisted by the King of Cochin and the ruling Zamorin of Calicut. Prominent among the Indian contributors were three Gouda Saraswat Brahmins named Ranga Bhat, Vinayaka Pandit, and Appu Bhat.
The ethnomedical original information in the work was provided by these three working on it for two continuous years morning and evening as certified by them. Their certificate to this effect is given in the first volume of the book
All the country around was diligently searched by the natives best acquired with the habitats of plants; and fresh specimens were brought to Cochin where the Carmelite Mathaeus sketched them, with such striking accuracy, that there was no difficulty in identifying each particular species when you see his drawings. Names of each species is written in Malayalam as well as Konkani (Then known as Brahmananchi Bhas) A description of each plant was written in Malayalam and thence translated into Portuguese, by a resident at Cochin, named Emmanuel Carneiro. The Secretary to Government, Herman Van Douep, further translated it into Latin, that the learned in all the countries of Europe might have access to it. The whole seems then to have passed under the supervision of another learned individual named Casearius, who was probably a Dutch Chaplain and a personal friend of Van Rheede. A book of its size, on which such care was expended, must have consumed a fortune before its publication, and confers honour, both on those who compiled it and the place where it was compiled.
The Hortus Malabaricus comprises 12 volumes of about 500 pages each, with 794 copper plate engravings. The first of the 12 volumes that comprise the book was published in 1678, and the last in 1703. It is believed to be the earliest comprehensive printed work on the flora of Asia and the tropics.Mentioned in these volumes are plants of the Malabar region which in his time referred to the stretch along the Western Ghats from Goa to Kanyakumari. The book gives a detailed account of the flora of Kerala, along with sketches and detailed descriptions. Over 742 different plants and their indigenous science are considered in the book. The book also employs a system of classification based on the traditions adopted by the pre-ayurvedic practitioners of that era. Apart from Latin, the plant names have been recorded in other languages viz. Konkani, Arabic and Malayalam.